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Pediatric - Cross-Eyed

Question:

May I please solicit some advice?

(first a detailed background and then 2 questions)

On Saturday morning, my daughter (2 years, 9 months) suddenly woke up...
cross-eyed.

We have been to a doctor and an ophthalmologist, and will see them again
in a few days, but I would like further input if it is possible, please.

There are two other issues:

  • At the age of 9 months, she fell from her crib and fractured her skull. There was slight bleeding beneath the skull. But all healed on its own.     There was never any fainting, vomiting or any symptom. She has been fine since.  The fracture was above HER right temple.

  • On Friday night (night before she woke up cross-eyed), she and I were playing games staring into each other's eyes (basically, going deliberately cross-eyed.

The ophthalmologist said that my daughter is slightly far sighted (unlike me
who is very near sighted), and the far sightedness is asymmetrical.  In such
cases, children try to compensate (hence the cross-eyed), and that it is
remotely possible that our cross-eye game the night before might have kicked
it in (but that I should not feel bad, I did not cause this, and it would
have
happened eventually).

Well the doctor wants us to get glasses for a few days, and if it all clears
up... likely that was it... if not... a CAT scan.

Now my wife's friend - who has good intent - has just told me:

1) It should be an MRI not a CAT scan.
2) the analysis above does not hold water... does not make sense
3) There may be damage to the sixth cranial nerve.

Answer:

Listen to the ophthalmologist.  Tell all doctors her history (but it seems totally unrelated).  It sounds sounds like Dr. has this diagnosis under control. 

We see 100 children each year like this and glasses are the proper treatment. Visit Signs of Vision Problems for more information.  This seems to be esotropia / crossed eyes  and coincidently happens at this age. This is more noticeable when child is tired or the focus is very close.  Glasses are the 'cure' for the problem 95% of the time.  Follow up is mandatory and further evaluation or testing is mandatory if clinically indicated or if problems worsen see your ophthalmologist.

Ask all doctors "what would you do for your own child"? 

Thanks again for the question, you did the right thing.....

Mark A. Sibley, MD, FACS
Lasik and Refractive Specialist
Cataract and Laser Specialist

Board Certified Eye Surgeon

727-895-2020

 

Pediatric - Squinting

Question:

I have a baby girl she is nine months old, from few weeks I have observed that whenever she feels sleepy her left eye gets squint towards the outer side only for few seconds and then she again becomes normal. I don't know if this is normal in this age or this is an issue which has to be taken care of.

Answer:

All babies eyes are learning to see objects and to follow the objects that they are learning to focus on. All babies eyes will seem to drift or wander at times, especially when they are tired or distracted.

The natural position of the eyes at those times of fatigue, etc. may be to drift apart, like you are describing.  Visit our Children's Eye Care section for more information.

It may be totally normal, BUT please mention it to your pediatrician.

If it continues or becomes more constant, insist on having your daughter seen by an eye doctor for a comprehensive eye exam. Comprehensive eye exams

Mark A. Sibley, MD, FACS
Lasik and Refractive Specialist
Cataract and Laser Specialist

Board Certified Eye Surgeon

727-895-2020

 

Pediatric - Child Blinks Eyes Frequently

Question:

I don't think anything is really wrong and I will have him looked at, but I'm looking for a little insight first.  My 3yr old son seems to be blinking both of his eyes unnaturally frequent.  When he blinks them he squints his face a little.  It almost looks intentional.  When I ask him he says his eyes do not hurt and I think his vision is fine.  Watching television or looking at flash cards. 

I have asked him several times if his eyes hurt and he says no.  and I know it's probably not related, but he say's and points to a drawing he made is making him do it.???  It's a complicated and busy artwork project.  He said it makes him tired?  Just 3 year old speak?

Any ideas or direction are greatly appreciated!

Answer:

While it is possible that your child is simply discovering the joys of controlling his eyes for the first time, it is perhaps equally likely that he may have discovered his focus improves during the act of squinting.  This could indicate a problem with astigmatism (a blurring of the light beams they enter the eye) anisometropia (inequality of focus between the two eyes), or early signs of nearsightedness.

I have seen similar cases where the only problem was "middle child syndrome."  Older siblings and younger siblings are perceived by the middle child to get "all the attention" and the middle child discovers that he can definitely boost his share of parental attention by doing safe but strange things like blinking the eyes too much.

A professional evaluation would likely be the best way of assuring that any legitimate problem is discovered and treated and that any "attention syndromes" are noted as such.

I hope this is helpful to you, and thanks for your question.

Florida Eye Center

727-895-2020

 

Pediatric Anisocoria Question

Question:

My son Leighton is 17 months and has had different size pupils in low light. Should I be concerned?  Thanks for your help on this.

Answer:

Unequal pupils is called anisocoria.

Approximately 10 percent of people have different-sized pupils (anisocoria). Your child should be examined by a pediatric ophthalmologist. There are simple medical tests to rule out certain causes of  anisocoria.  Children's Eye Care

These tests could be done by the Ophthalmologist and usually involve the use of drops in the office.

The ophthalmologist should carefully evaluate the vision and motility. The most important consideration is to determine if amblyopia is present. Signs of Vision Problems

Amblyopia ( Lazy Eye) in children with anisocoria may be increased. There may also be a possibility of strabismus (crossed eyes), emphasizing the need for careful motility examination in these patients .Children's Eye Exam

Assessing for amblyopia in an infant can be difficult. Children with good vision in only one eye may function and behave just as well as a child who has perfect binocular visual acuity. Therefore, vision should be assessed in each eye independently.

The presence of anisometropia is a possible cause of amblyopia. correction. Early cycloplegic refraction must be performed in patients to detect any anisometropia and spectacles prescribed as necessary. In general, a difference of 1.25 to 1.50 D of astigmatism is considered amblyogenic.

Sometimes the abnormality is not the larger pupil but the smaller one. Without knowing the exact cause, I can't say whether it is normal or not. Even if there is a problem, it could eventually become normal.

One possible cause could be Horner's Syndrome.

Horner's syndrome is a triad of features resulting from interruption of the sympathetic pathway from the hypothalamus to the orbit, as follows:

  • slight ptosis

  • pupillary miosis:

    • due to paralysis of the sympathetically innervated Muller's muscle which normally dilates the pupil

  • anhydrosis (no sweating) over the forehead

Horner's syndrome is associated with several other syndromes:

Congenital Horner's syndrome may be associated with congenital heterochromia of the iris

Horners Syndrome

Question: How is Horners syndrome detected? What is the treatment for Horner's syndrome? What is the cause?

Answer: Horners Syndrome is caused by damage or interruption of the sympathetic nerve to the eye. This causes a small, regular pupil; ptosis (drooping) of the eye lid on the same side; and occasionally loss of sweat formation on the forehead of the affected eye. The pupil will still react to light stimulus and will accommodate to distant vision. The pupil of Horners Syndrome will not enlarge in the dark. Treatment for Horners Syndrome focuses on finding the cause of the interruption of the sympathetic nerve to that area of the eye. This is usually in the neck, but can be in the brain.

Other possible causes of Anisocoria

Anisocoria is a cause of concern for any clinician since some of the associated conditions are sight- or even life- threatening. The first step towards a correct diagnosis is to determine if the pupillary response in each eye is normal.

Physiologic anisocoria: the majority of patients with anisocoria have a physiologic difference in the size of the two pupils. The patient usually has no symptoms and may not be aware of the difference. Response to light and near testing is usually normal and difference in size of the two pupils is usually less than 2mm.

Horner’s syndrome: can be congenital or acquired (trauma, surgery, migraine, stroke, lung tumors, and demyelinating diseases). Ptosis, miosis, and facial anhydrosis are noted in Horner’s syndrome; the congenital disease is also associated with iris heterochromia. Response to light and near testing is usually intact although anisocoria is greater in dim light. Instillation of 1-% hydroxyamphetamine is used to determine the location of the lesion.

Iritis: can be traumatic, idiopathic, or associated with systemic disease. Patients usually complain of pain, photophobia, and red eye. Cells and flare are noted in the anterior chamber and ciliary injection is usually present; posterior synechiae can also develop.

Argyll-Robertson pupil: is a light-near dissociative response most commonly associated with neurosyphilis. It is usually bilateral and patients do not experience symptoms directly related to it. Pupils are assymetrical, irregular, and react poorly to light but constrict normally to a near stimulus.

Pharmacologic miosis: most commonly secondary to unilateral instillation of a miotic drop for the treatment of glaucoma. Pupil will react poorly to light and pharmacologic dilatation.

Traumatic pupillary rupture: patient usually has no symptoms; there is a history of trauma and the slit–lamp exam reveals iris atrophy, sphincter rupture, or synechiae in the affected eye.

Adie’s tonic pupil: more common in females and usually patient is asymptomatic. Most cases are idiopathic but associations are present with viral infections, neuropathies, or trauma. Pupil is fixed and dilated with poor response to light and near. Depressed deep tendon reflexes are also associated with this condition.

Acute angle-closure glaucoma: patients with ACG usually complain of eye pain, blurred vision, haloes, and nausea. Exam reveals an edematous cornea, IOP is elevated, pupil is fixed mid-dilated, and gonioscopy reveals a closed angle.

Pharmacologic mydriasis: common culprits include the use of mydriatic agents, scopolamine patches for motion sickness, and contact with belladona plants.

Third nerve palsy: sudden ptosis, diplopia, and pain are some of the symptoms of CN III palsy. Pupil is fixed-dilated, and extraocular motility will be restricted.                                                          

MANAGEMENT
In general, the treatment for Horner's syndrome depends upon the cause. In many cases there is no treatment that improves or reverses the condition.

Treatment in acquired cases is directed toward eradicating the disease that is producing the syndrome. Recognizing the signs and symptoms is tantamount to early diagnosis and expedient referrals to specialists.

Horner's syndrome has no predilection for age, race, gender or geographic location. Horner's syndrome of congenital origin is typically around the age of two years with heterochromia and absence of a horizontal eyelid fold or crease in the ptotic eye. Iris pigmentation (which is under sympathetic control during development) is completed by the age of two, making heterochromia an uncommon finding in Horner's syndromes acquired later in life. Old photographs can aid the clinician in distinguishing congenital Horner's by documenting heterochromia present at, or near, birth.

CLINICAL PEARLS

  • The time frame for testing is important because cocaine has the ability to inhibit the uptake of Pholedrine and Paradrine into the presynaptic vesicle, reducing accuracy. There must be at least 48 hours between the tests.

  • Some of the older literature suggests employing Phenylephrine 1% solution for localization. This technique is rarely employed because patients with either preganglionic or postganglionic lesions become hypersensitive to the drug making results inaccurate.

  • There is a "dilation lag" in Horner's syndrome where the involved pupil will dilate slowly in dim illumination. That is, the degree of anisocoria diminishes as the patient sits in a dark room.

  • Post-ganglionic Horner's syndromes tend to occur from more benign causes and are typically vascular in origin.

  • If hemianalgesia and/or hemiparesis appear with Horner's syndrome, then the lesion is within the spinal cord or brain.

  • Isolated Horner's syndrome typically is vascular in nature.

I hope this information was helpful. Please save and discuss this with your baby's doctors.

 

Mark A. Sibley, MD, FACS
Lasik and Refractive Specialist
Cataract and Laser Specialist

Board Certified Eye Surgeon 727-895-2020

 

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